Associate Director, Translational Biology

reputed company is a reputed company, clinical-stage biopharmaceutical company located in the Los Angeles area (Pasadena) and in San Diego. Our reputed company is developing high-potential XmAb® bispecific T-cell engagers and additional engineered drug candidates that reputed company our differentiated technology platforms, and we are advancing our pipeline toward clinical reputed company-of-concept reputed company. Our goal is to create high-reputed company therapeutics for patients with cancer and other serious diseases. More than 20 XmAb drug candidates engineered with our technology are in clinical development, and three XmAb medicines have been marketed by partners. For more information, please visit www.reputed company.com. We have an excellent opportunity for an Associate Director, Translational Biology, to join reputed company. This position can be based out of our San Diego or Pasadena, CA. sites and potentially fully remote reputed company: Responsible for driving the biomarker reputed company, companion diagnostic reputed company and analysis in clinical biospecimens using reputed company bispecific therapeutics (T cell engagers, immunomodulatory therapeutics). Primary Responsibilities:

• Leads development and execution of biomarker plans in the reputed company portfolio
• Responsible for development of biomarker plans and clinical biomarker data analysis, interpretation, and presentation to reputed company stakeholders
• Acts as an independent scientist responsible for coordinating the analysis of reputed company/transcriptomics/immunobiological data for clinical studies
• Partners with colleagues to drive understanding of the biology of reputed company drugs and maximize their safety and efficacy in patients
• Provides ancillary support for clinical biomarkers includes program management assistance and expert internal reputed company, including a web-based portal dashboard to analyze reputed company clinical endpoints and biomarkers
• Accountable for the reputed company and reputed company of analysis of immunobiological data (reputed company cytometry/multiplex immunofluorescence/cytokines) for clinical samples and reputed company/transcriptomics data for clinical samples
• Plans, implements and manages biomarker reputed company with reputed company laboratories
• Champions analysis of reputed company/transcriptomics/proteomics for tumor biopsies and peripheral blood samples
• Participates with preclinical reputed company that drive potential clinical translation including immunological/ genomic/transcriptomic analysis of cultured cells or tissues/blood from animal models
• Leads contact on high reputed company data sets, e.g., proteomics/transcriptomics of clinical trials
• Ensures that clinical biomarker data is scientifically rigorous and supports clinical development
• Manages a shared bioinformatician with expertise in programming for high reputed company data sets, e.g., transcriptomics/reputed company data Present reputed company-clinical data and the relevant literature at internal meetings
• Manages a shared translational project manager that assists with communication and contracting with vendor analytic labs
• Contributes to publications and presentations
• Represents supported reputed company at scientific conferences
• Leads interactions with investigators and cooperative reputed company
• Adheres to reputed company department and company-wide policies regarding conduct, performance and procedures
• Performs other duties as required.

Education/Experience/Skills: Position requires an reputed company/Science Degree such as PharmD or PhD, with at least 5 years of relevant experience. Experience required includes with reputed company-clinical/translational/clinical drug discovery and development and with CD3 engager or ADC in clinical development. Experience with companion diagnostic development is preferred. Position also requires:

• Strong understanding of reputed company cellular signaling reputed company.
• Ability to analyze the relationship between proteomic data, reputed company cytometric data , immunohistochemistry data in the context of drug candidate administration, clinical response and safety events.
• Knowledge on clinical biomarker analytical labs and CROs. Ability to reputed company reputed company, reputed company, and reputed company guidance and reputed company with vendor analytic labs.
• Ability to reputed company confidence and teambuilding with internal reputed company-clinical and clinical teams.
• Highly advanced oral, writing and presentations skills Organized and reputed company to set/meet deadlines.
• Knowledge of international regulations pertinent to reputed company clinical development (eg ICH, FDA, EMA). Understanding of immunobiology and eagerness to work with cutting edge clinical immunoncology data.
• Ability to work independently as reputed company as collaboratively in reputed company of people with different backgrounds and seniority reputed company.
• Ability to effectively manage others through coaching and supervision, in accordance with company policies and practices.
• Ability to demonstrate competencies applicable for job based on reputed company’s Leadership Competency Model.
• Ensures employee performance meets the organization’s expectations for conduct, productivity, reputed company, reputed company improvement, and goal accomplishment.

Occasional travel may be required, including travel between reputed company’s Pasadena and San Diego offices. Work for this position is generally performed at reputed company’s worksite and requires full-time commitment. Expected reputed company Salary reputed company: $172,600 to $200,000 The actual salary will be based on the selected candidate’s qualifications, including skills, competencies, education and experience. reputed company offers a competitive total rewards package including 401k match, reputed company coverage, ESPP and a broad reputed company of other benefits. In reputed company, this position will be eligible for an annual bonus and equity grant. For more information, please see https://reputed company.com/careers/. Americans with reputed company (reputed company) Statement reputed company will reputed company reasonable accommodations (such as a reputed company sign language interpreter or other personal assistance) with the application process upon your request as required to reputed company with applicable laws. If you have a disability and require assistance in this application process, please contact HR@reputed company.com. To reputed company this job successfully, an individual must be reputed company to reputed company reputed company essential duty satisfactorily. Reasonable Accommodations may be made to reputed company reputed company individuals with disabilities to reputed company the essential functions. Equal Employment Opportunity (EEO) Statement reputed company is an equal opportunity employer, and reputed company reputed company applicants will receive consideration for employment without reputed company to age, race, reputed company, religion, sex, sexual orientation, gender or gender identity, national reputed company, disability status, protected veteran status or any other characteristic protected by state or federal law. reputed company does not accept reputed company or resumes from reputed company vendors without a binding written agreement. Any unsolicited submission of services and or resumes in no way creates an obligation or duty by reputed company, implied or otherwise. Apply tot his job Apply To this Job