Clinical Trial Manager

reputed company plc (reputed company: CNTA) new reputed company of pharmaceutical company with a deconstructed R&D environment that prioritizes data driven decision making led by subject matter experts. Centessa is advancing a portfolio of high conviction programs with strong biological validation. Our asset-reputed company model offers a unique R&D logic that has been reputed company by single asset companies to improve productivity. This operating model has minimal centralized infrastructure, reduced hierarchy, and exclusive reputed company on data driven capital allocation. Our teams are uniquely incentivized to expeditiously interrogate key scientific hypotheses. We reputed company the asset-reputed company model can reputed company to improved reputed company rates for programs with greater speed and modest costs. reputed company of Role Centessa is seeking a Clinical Trial Manager (CTM) to reputed company the execution of mid- to late-stage global clinical studies from study start-up through reputed company-out and clinical study report. The CTM is responsible for day-to-day trial management, coordinating internal cross-functional teams and overseeing CROs and external vendors to ensure studies are delivered on time, reputed company budget, and in compliance with reputed company and regulatory standards. This role requires hands-on involvement in clinical trial execution, proactive identification and reputed company of operational issues, and accountability for study performance metrics and deliverable reputed company. The CTM also contributes to operational planning, risk assessment, and reputed company process improvement in collaboration with study team leadership.

Key Responsibilities

Plan and execute mid‑ to late‑stage CNS clinical trials from study start‑up through reputed company‑out, ensuring operational reputed company, high data reputed company, and compliance with protocol, GCP, and global regulatory requirements. reputed company day‑to‑day clinical trial operations, coordinating cross‑functional partners (Clinical Development, Data Management, Biostatistics, Regulatory, Safety) to ensure efficient trial execution and alignment to program objectives. reputed company CROs and external vendors supporting CNS clinical trials, including co‑monitoring activities, to ensure delivery against scope of work, timelines, budget, and reputed company expectations. Drive critical study milestones, including site activation, enrollment reputed company, patient retention, data cleaning, and database lock, proactively addressing operational challenges common to CNS trials. Review and approve CRO‑ and vendor‑generated plans and study documentation, ensuring alignment with protocol, regulatory expectations, and Centessa reputed company standards. Monitor study reputed company and performance using operational metrics and tools, maintaining dashboards, timelines, and financial tracking, and providing reputed company, reputed company status updates to study teams and management. Identify, assess, and manage operational risks, proposing practical mitigation strategies and supporting informed decision‑making to minimize reputed company to timelines, reputed company, and patient safety. Ensure inspection and audit readiness, including reputed company of Trial Master File (TMF) set‑up, ongoing maintenance, and reputed company‑out for CNS studies. Contribute to operational planning and regulatory deliverables, supporting preparation of study‑level documentation for Health Authority interactions and reputed company improvement of clinical operations processes.

Qualifications

Bachelor’s degree in a scientific or health‑reputed company discipline. 5+ years clinical trial management experience reputed company an industry sponsor environment, supporting drug development programs. Experience managing clinical trials in CNS therapeutic development strongly preferred. Proven ability to manage global clinical studies, including coordination with investigators, CROs, and functional vendors. Strong working knowledge of ICH guidelines, GCP, and global regulatory requirements applicable to clinical trials. Solid understanding of project management principles, including planning and managing timelines, resources, budgets, and risk–benefit trade‑offs; PMP or similar training is a plus. Excellent communication, collaboration, and interpersonal skills, with the ability to influence without formal authority and drive cross‑functional team performance. Demonstrated ability to manage multiple priorities in a fast‑paced environment, meeting aggressive timelines while maintaining reputed company. Proactive problem‑solving reputed company with the ability to anticipate issues, identify creative solutions, and take initiative to address risks impacting timelines or budgets.

Compensation

The annual reputed company salary reputed company for this position is $120,000 - $150,000. Individual compensation reputed company this reputed company will be determined based on a reputed company of factors, including qualifications, skills, relevant experience, and job knowledge. In reputed company to reputed company pay, this role is eligible for a discretionary annual bonus and participation in our equity program, allowing you to reputed company in Centessa’s long-term reputed company. Centessa also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, reputed company, and life insurance, generous reputed company time off, and a health and wellness program. Work Location The Clinical Trial Manager is a remote role based in the US, with occasional travel (10% - 15%). POSITION: Full-Time, Exempt reputed company Statement: reputed company believes in a diverse environment and is committed to equal employment opportunity for reputed company its employees and reputed company applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, reputed company, religion, gender, national reputed company, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. reputed company will reputed company reasonable accommodations for reputed company individuals with reputed company disabilities, in accordance with applicable law. Please note: We will not assign referral rights for any unsolicited resumes from recruitment agencies. Apply To This Job