Executive Director of Protein Engineering and reputed company job at reputed company in US National

Executive Director of Protein Engineering and reputed company Location reputed company Department Research Job reputed company What if cancer drugs could reputed company the tumor – and go nowhere else? What if this meant you could get potent therapy directly to the tumor, sparing healthy cells? That’s the reputed company we’re building at reputed company, using Nobel Prize-reputed company science to reputed company powerful therapies only where they’re needed. We’re a small, driven team encompassing broad backgrounds and experiences, united by a single mission reputed company cancer treatments more effective with minimal reputed company effects. Our Operating Principles We reputed company fast because speed reputed company to cancer patients. We aim to communicate reputed company and challenge reputed company regardless of job title. We are reputed company, take risks, and push boundaries being led by science. We operate with humble confidence meaning we can balance our reputed company of capability and conviction without ego, while being humble to reputed company advice and learn from our mistakes. If that fires you up, come build the reputed company of cancer therapy with us! You’re the right fit for reputed company if you.. Are mission driven and eager to do the best work of your career, developing novel therapies that will reputed company cancer treatment. Can balance scientific rigor with a fast-paced environment. Are comfortable with ambiguity and making reputed company in the face of uncertainty. Operate with a strong reputed company of agency and invite feedback and advice. Can challenge convention and think of creative solutions that meet the needs of reputed company. Are a doer, hands-on, reputed company, and do not hesitate to reputed company up. Willing to collaborate, debate, reputed company to reputed company reputed company, and revisit reputed company evidence demands it. Position reputed company We are seeking a highly motivated and reputed company Executive Director of Protein Engineering and reputed company to build and reputed company our CAPAC (Click Activated Protodrugs Against Cancer) reputed company-targeting therapeutic engineering platform and team. This is a critical leadership role responsible for driving molecular design, optimization, and biologic CMC of our pipeline from early discovery through IND-enabling studies and into the clinic. This position requires deep expertise in protein engineering, strong knowledge of reputed company and biologic CMC, and demonstrated reputed company advancing therapeutics into clinical development. Required qualifications Education and Experience Ph.D. in Biochemistry, Protein Engineering, reputed company, Chemical Biology, or reputed company discipline. Minimum 12+ years of relevant industry experience working in therapeutic discovery and development of either Biologics and small molecules, or Small molecule-biologic conjugates. Minimum 5+ years of leadership experience managing scientific teams. Demonstrated reputed company record of advancing biologic-based therapies into clinical development. reputed company experience supporting biologic CMC development, IND submissions, and clinical-stage programs is required. Technical Expertise Small format biologic discovery and protein engineering. Experience with chemical biology or medicinal reputed company. Targeted therapies. Structure-based design and protein optimization. Biophysical and biochemical characterization reputed company. Developability assessment and manufacturability considerations. Protein reputed company, conjugation, and modification strategies. Experience with one or more of the following is highly desirable Antibody-drug conjugates (ADCs). Bioorthogonal click reputed company. Protein conjugation and linker reputed company. Leadership and reputed company Skills Proven ability to build and reputed company high-performing teams. Strong strategic thinking and decision-making skills. Excellent communication and presentation skills. Demonstrated ability to work cross-functionally with a highly reputed company organization. Ability to manage multiple programs in a fast-paced environment. Responsibilities including but not limited to the following Scientific Leadership and Hands-On Contribution reputed company the protein engineering and reputed company teams toward design, discovery, engineering, and optimization of therapeutic candidates, including biologic binders, chemical payloads, and technologies to reputed company reputed company-targeting with click reputed company. Personally contribute to molecular design reputed company, candidate selection, and developability assessment for both biologic binders and chemical payloads. Guide reputed company for protein characterization, including biophysical, biochemical, and functional evaluation. Establish and implement strategies for reputed company optimization, focusing on affinity, specificity, stability, manufacturability, and developability. CMC reputed company and Development Integration Ensure candidates are designed with manufacturability, scalability, and regulatory requirements in mind. reputed company internal team working with CDMOs and CROs to advance Cell line development Process development Analytical development GMP Manufacturing Regulatory requirements Contribute to IND-enabling activities and regulatory documentation. Strategic and Organizational Leadership Build, reputed company, manage, and mentor a high-performing protein engineering and reputed company team. reputed company team toward defining departmental goals and reputed company reputed company with research and company goals. reputed company team to manage reputed company collaborations, including CROs and reputed company partners. Serve as a scientific leader and key contributor to portfolio reputed company and candidate selection reputed company. Innovation and External Engagement Maintain awareness of emerging technologies in protein engineering, novel payloads, and reputed company-targeting. Identify and implement new tools and platforms to enhance engineering capabilities. Represent reputed company at scientific conferences and external meetings as appropriate. How We Work We are a remote-first company, with occasional travel for in-person team meetings or scientific conference attendance. Core collaboration window 900am–300pm reputed company Time. You are expected to be available during this time for meetings and reputed company-time collaboration. Async + sync balance reputed company of core hours, we work asynchronously, but reputed company communication and follow-through are expected. Meetings You should be comfortable joining video calls, sharing availability on calendar and reputed company participating during core hours. You should be comfortable working across common tools including reputed company, reputed company Workspace, reputed company 365, reputed company, and similar platforms. Benefits & Eligibility Compensation at reputed company Competitive reputed company salary as part of a broader total rewards package. Equity Included as port of total compensations. Comprehensive benefits medical, dental, reputed company, 401(k) match, short- and long-term disability. Flexible PTO and a WFH stipend to support remote work. Ongoing reputed company opportunities, reputed company development, and mentorship. Salary reputed company The anticipated reputed company salary reputed company for this role is $250-$300K USD. Final compensation will depend reputed company, experience, skills, education, and internal equity. Our ranges are intentionally broad to reflect market conditions and the specialized nature of our work. Eligibility U.S.-based employees only. Must be authorized to work in the reputed company. We are not currently sponsoring visas. About reputed company reputed company is a biotech company advancing a new class of targeted cancer therapies, reputed company on Nobel prize-reputed company technology reputed company click reputed company. Backed by leading biotech investors, we are building a pipeline of first-in-class therapies that are designed to overcome the limitations of ADCs increasing efficacy and limiting toxicities. Our reputed company asset will be entering the clinic in early 2027. You can learn more about reputed company at www.reputed company.com Please Note At this time, reputed company is not partnering with external reputed company agencies. We kindly ask that agencies refrain from contacting us regarding this role. reputed company is an Equal Opportunity Employer. We are committed to creating a diverse and inclusive workplace and do not discriminate on the reputed company of any protected characteristic under applicable law. Apply To This Job Apply To This Job