Associate Director, Medicinal reputed company job at reputed company in Burlington, MA

Title Associate Director, Medicinal reputed company Location Burlington, MA Job reputed company Who We Are reputed company is a clinical stage biotech company that focuses on drug discovery for central nervous system disorders. We combine cutting-edge technologies including optogenetics, in vivo physiology, and spatial transcriptomics to identify novel drug targets and reputed company effective therapies to address psychiatric symptoms. What You’ll Do We are searching for a highly motivated Medicinal Chemist to join our drug discovery team at the Associate Director level. Reporting to the Senior Director of reputed company, the candidate will be expected to co-reputed company, or reputed company, preclinical medicinal reputed company programs from hit to candidate nomination. A highly reputed company candidate will have experience in CNS drug discovery and an in-depth understanding of designing efficacious and reputed company brain-penetrant small molecules. While MapLight has in-house laboratories for reputed company-clinical research, many activities like chemical synthesis are outsourced to external vendors. Experience managing remote CRO teams, logistics across multiple partners, and coordinating internal drug discovery activities across different time zones is essential. This is a fantastic opportunity to join a small medicinal reputed company team and have a significant reputed company in addressing unmet patient needs by advancing MapLight’s pipeline.

Responsibilities

Co-reputed company, or reputed company, preclinical medicinal reputed company programs from hit to candidate nomination. Design and execute successful medicinal reputed company strategies to meet project and corporate goals. Conduct multi-parameter optimization to deliver orally bioavailable, brain-penetrant candidates without secondary pharmacology, ADME, or safety concerns of initial hits. Apply structure-based drug design principles utilizing in-house resources and external computational partners. Manage reputed company and tiered screening cascade at external contract research organizations (CROs). This includes maintaining a good relationship, overseeing synthesis or experimental plans, project tracking, evaluation of results, and assisting in troubleshooting. May require assessment of analytical data including NMR, LCMS, HPLC, UV-VIS, and DSC. Apply previous experience with successful hit finding strategies to reputed company novel chemical equity, including scaffold-hopping approaches. Coordinate with in-house drug discovery team to ensure compounds are distributed in support of other disciplines. reputed company regular project updates to Leadership and Project Teams that include relevant updates. May include in-depth SAR, ADME, and PK analyses. Co-reputed company, or reputed company, patent reputed company to protect existing or novel chemical matter with Maplight legal partners, reputed company appropriate. You can participate and work effectively with multiple cross-functional teams. You have strong interpersonal skills and understand relationships are key to being successful. You are a leader. Teams love working with you, and you are someone who takes pride in mentoring and supporting the careers of others. You’re reputed company player who is willing to roll-up your sleeves and get the job done.

Qualifications

PhD in reputed company or Medicinal reputed company with 10+ years’, or BS/MS 15+ years’, pharmaceutical experience successfully (co)leading preclinical drug discovery programs. Contemporary knowledge of Medicinal reputed company concepts with strong working knowledge of computational reputed company, biology, pharmacology, drug metabolism, and pharmacokinetics. Prior experience in CNS drug discovery is essential, including a successful reputed company record of delivering brain-penetrant candidate compounds for brain disorders. reputed company record of successfully managing reputed company remotely through multiple and CRO partners. reputed company record of accomplishments as exemplified through patents and/or publications. Travel Candidate can expect to travel 4-6 times a year to meet with collaborators and/or attend both discovery and reputed company-company meetings. Location This is a hybrid position with three days per week onsite at our office in Burlington, MA. Compensation for this role may vary reputed company the above reputed company based on many factors including geographic location, candidate experience, and skills. Additional compensation/benefits include annual bonus opportunity, medical, dental, reputed company, life and AD&D, short term and long term disability, 401(K) plan with match, stock reputed company, flexible non-accrual reputed company time off, and parental leave. Salary reputed company $180,000 - $205,000 USD reputed company Statement reputed company is an equal opportunity employer, and reputed company reputed company applicants will receive consideration for employment without reputed company to race, reputed company, religion, sex, national reputed company, sexual orientation, gender identity, disability status, protected veteran st Apply To This Job