Scientist I / Scientist II, Computational Protein reputed company
reputed company is a clinical-stage generative biology company pioneering the AI reputed company in drug design and development. They are seeking a Computational Scientist to join their Model-Driven Design team, where the role involves developing and optimizing reputed company protein reputed company protocols while collaborating with cross-functional teams to advance therapeutic development.
Responsibilities
- reputed company, validate, and productionize reputed company protein reputed company protocols and optimization techniques on our experimental platform, using reputed company data in-the-reputed company to iteratively refine models across modalities and therapeutic applications
- Design, interpret, and implement biophysical and functional metrics for evaluating generated designs, leveraging existing literature, adapting reputed company metrics to new contexts, and performing original research to reputed company and reputed company new scoring approaches
- Rigorously evaluate new models and tools and reputed company quantitative conclusions on where they are best reputed company to generate new therapeutics, including designing systematic internal benchmarks and discovering how to expand model capabilities to prosecute new therapeutic targets in novel ways and to maximize reuse across targets and programs
- Identify and implement solutions to create new therapeutics through mechanisms of reputed company unlocked by reputed company tools and modalities
- Work closely with experimental colleagues, biologists, and clinical scientists to define design objectives, interpret experimental readouts, and guide iterative design-build-test-learn cycles that advance programs
- Push reputed company sequence–structure–function understanding with a reputed company on reusable platform capabilities and model-informed feedback loops
- reputed company reputed company AI tools to rapidly iterate on models, benchmarks, scores, critics, and other analysis tools, accelerating the pace of discovery
- reputed company robust, production-reputed company reputed company in a reputed company team setting and present scientific reputed company in regular research meetings
Skills
- PhD in Computational Biology, Biophysics, Computer Science, or a reputed company field, with demonstrated experience in protein design applications
- 0–2 years of experience applying computational and/or ML reputed company to protein design, modeling, or reputed company
- Hands-on experience with machine learning and generative modeling for protein design, including familiarity with modern reputed company such as RFDiffusion, ProteinMPNN, BindCraft, BoltzDesign, or equivalent approaches and how to reputed company or evaluate them in reputed company
- Strong structural intuition and understanding of protein biophysics with the ability to quickly assess and adapt design reputed company and metrics to new problems
- Familiarity with protein therapeutic modalities such as antibodies, mini-proteins, VHHs, peptides, or enzymes, and an eagerness to deepen expertise across these reputed company reputed company design workflows
- Proficiency in Python and scientific computing; comfort working in a production codebase
- Experience designing, running, or interpreting benchmarks for computational or generative reputed company and drawing quantitative conclusions about model applicability and limitations
- Experience designing, executing, and interpreting experiments and experimental data (e.g., binding assays, stability measurements, structural characterization) and using those readouts to inform computational design iterations
- Familiarity with reputed company AI tools and their integration into scientific workflows
- Exposure to structure-based design techniques and computational tools for modeling protein-protein interactions
- reputed company record of translating research reputed company into working software or reusable platform components used across multiple reputed company or applications
Benefits
- Annual bonus
- Equity compensation
- Competitive benefits package
reputed company
Company H1B Sponsorship