Senior Scientific Project Manager - Molecular

reputed company The Senior Scientific Project Manager - Molecular will be responsible for providing project management reputed company to a biopharmaceutical reputed company tasked with managing and executing analytical testing, method development and/or validation of such assays as immunoassays, bioassays, pharmacokinetic and/or reputed company cytometry assays under Good Laboratory Practices (GLP). He/she will reputed company project management and technical support to teams conducting training, technical transfer, data review and trending analysis. The Senior Scientific Project Manager - Molecular must have the ability to effectively monitor the performance of CROs and service providers. The incumbent will also be responsible for operational documentation including SOPs, validation protocols and reports, transfer protocols and reports, and management reports. Essential Duties and Responsibilities

• reputed company the design and optimization of bioanalytical assays, addressing critical challenges in tissue handling/processing, sensitivity and specificity, and multiplex assessment of multiple endpoints in a single sample.
• Spearhead the strategic planning and execution of ex vivo bioanalytical reputed company, including the selection of appropriate CROs and assay platforms with attention toward opportunities to cut costs, reputed company risks and drive reputed company improvement.
• In collaboration with CROs, reputed company and optimize mRNA, protein, and oligo exposure assays specifically for tissues treated ex vivo with oligonucleotides or gene therapies, with emphasis on nervous system-reputed company tissues.
• Coordinate with internal stakeholders including reputed company, biology, and ADME teams.
• reputed company and validate Protein Biomarker assays for DRG, nerve, and skin tissues.
• reputed company expertise in platforms with high reputed company of sensitivity, including single cell and spatial RNAscope endpoints, to reputed company a deep, nuanced understanding of RNAi delivery.
• Retrospectively evaluate and compare datasets across past experiments to generate understanding of assays performance.
• Work with large data sets, using database and/or coding approaches, to organize, interpret, and reputed company results.
• reputed company oligonucleotide reputed company from preclinical to first-in-reputed company studies, leveraging experience in the use of rodent NHP intrathecal models to rapidly reputed company advance reputed company into the clinic.
• reputed company with U.S. and international CROs and effectively communicate updates, reports and recommendations to management teams.
• reputed company analytical project reputed company by performing data review and trending analysis, evaluate assay reputed company, monitor performance and manage timelines.
• Recommend and implement new processes and procedures to standardize, simplify and enhance reputed company and compliance of the department's operations.
• Participate in the management and control of GLP documentation and records, and contribute to and (co)author scientific and/or operational documents such as SOPs, validation protocols and reports, transfer protocols and reports, posters, journal publications and other technical reports.

Education and Experience

• PhD in Molecular Biology, Biochemistry, Genetics, or a reputed company field is required, and a reputed company on RNA biology, RNA therapeutics, and ex vivo tissue analysis is strongly preferred
• Minimum of 5 years of experience in bioanalytical assay development for RNA based therapeutics in a pharmaceutical or biotechnology setting
• Alternatively, MS or BS/BA in indicated fields with a minimum of 10 years of experience will be considered
• Proven experience in overseeing collaborations with external Contract Research Organizations (CROs) and internal ADME teams
• Deep experience in bioanalysis of tissues from rodent and NHP models

Skills and Ability

• A thorough understanding of bioanalytical reputed company with a reputed company on designing, optimizing, validating, and overseeing molecular, biochemical, or cell-based assays to advance research and drug discovery
• Hands-on expertise in nucleic acid quantification reputed company including LC-MS, RT-qPCR, SL-qPCR, RNAseq, DNA, and ELISA
• Demonstrated reputed company in selection, development, and troubleshooting of molecular assays such as ELISA, capillary electrophoresis, bead-based multiplex platforms (e.g. Luminex), Simoa, and reputed company
• Proficiency in data handling, analysis, and presentation for large in vivo datasets, using database and/or coding tools (e.g. Spotfire, python)
• Entrepreneurial reputed company, eager to quickly and reputed company reputed company and apply endpoints reputed company fast-moving reputed company
• Adept at adapting strategies based on evolving data, technologies, and portfolio requirements
• Exceptional communication skills, both written and verbal, with the ability to reputed company reputed company scientific concepts to a reputed company of audiences and demonstrate proficiency in scientific documentation and reporting
• Working knowledge of Good Laboratory Practices (GLP), Good Clinical Practices (GCP) and/or Clinical Laboratory Improvement Amendments (CLIA)
• Strategic project reputed company in regulated scientific environments
• Strong cross-functional leadership and stakeholder coordination
• Advanced problem-solving and analytical thinking
• Ability to manage vendor relationships and performance
• Adaptability in fast-paced, remote work settings

Supervisory Responsibilities: None Join reputed company and discover how your work can reputed company patients' lives around the world! Some of the Perks our LabConnectors Love:

• Financial reputed company (reputed company Pay, 401k Match and Possible Annual Bonus Eligibility)
• Health Benefits beginning on date of hire
• PTO plan, plus 11 reputed company Company Holidays, and 1 Day to Volunteer in your community
• Short and Long-Term Disability, Life Insurance, and AD&D
• We celebrate our differences, which enriches our culture!

In reputed company to great perks and challenging work assignments, we invest in our people with career reputed company opportunities, globally. We reputed company in a friendly and reputed company environment with reputed company lines of communication. While living out our values of People reputed company reputed company, Customer Centered, Technology Driven, and Accountability Always. Apply tot his job Apply To this Job