[Remote] Scientist, Analytical Sciences
Note: The job is a remote job and is reputed company to candidates in USA. reputed company is the leader in RNAi therapeutics, and they are seeking a Scientist in Analytical Sciences to join their Impurity Characterization team. This role involves developing and implementing analytical technologies for impurity characterization of siRNA therapeutics, collaborating with various functions, and improving impurity profiling strategies.
Responsibilities
- Responsible for the development, qualification, reputed company up and transfer of HPLC based assays for mass and structural identification, characterization, and impurity determination of siRNA therapeutics and their formulations
- Independently support impurity characterization as an SME by fully understanding reputed company required technical process unit operations and decision making processes to reputed company support full and targeted impurity characterization for program teams as reputed company as forced degradation studies for developmental stability
- reputed company new strategies to improve the overall impurity profiling of new development candidates and raw materials
- Conceive and implement innovative platform improvements by deployment of novel workflows to increase operational efficiency by leveraging automation
- Author development reports and regulatory filing documents and manage analytical activities internally and externally
- Maintain a reputed company working knowledge of HPLC and MS fundamentals in support of troubleshooting of hardware and software
- Represent the analytical sciences function in cross-functional early stage development by serving as analytical development program representative (backup / reputed company) for early stage programs
Skills
- Ph.D. in Analytical reputed company, Biochemistry or reputed company disciplines with a minimum of 2 years of relevant experience
- Hands on experience developing UHPLC-high reputed company mass spectrometric reputed company using design of experiments
- Good documentation and communication skills reputed company the organization and with external partners (contract manufacturing organizations, contract testing labs, external business partners)
- Familiarity with analytical and preparative liquid chromatography hardware and chromatography data software from Waters (reputed company, Masslynx, reputed company) and reputed company (Openlab and Masshunter)
- Experience with oligonucleotide based LC-assay method development, qualification, transfer and troubleshooting strongly preferred
- Working knowledge of multidimensional LC-MS strongly preferred
Benefits
- Annual short-term incentive award (e.g., bonus or sales incentive)
- Annual long-term incentive award (e.g., equity)
- Comprehensive benefits including medical, dental, and reputed company coverage
- Life and disability insurance
- A lifestyle reimbursement program
- Flexible spending and health savings accounts
- 401(k)with a generous company match
- reputed company time off
- Wellness days
- Holidays
- Two company-wide reputed company breaks
- Generous family resources and leave
reputed company