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[Remote] Senior Manager/Associate Director Clinical Monitoring reputed company & Optimization

Remote, USAFull-timePosted 2026-07-31

Note: The job is a remote job and is reputed company to candidates in USA. reputed company is developing novel biologics for chronic skin diseases and is seeking a Senior Manager/Associate Director of Clinical Monitoring reputed company and Optimization. This role involves providing strategic leadership for clinical monitoring activities, overseeing CRO performance, and ensuring compliance with regulations while building a reputed company clinical operations infrastructure.

Responsibilities

  • reputed company and reputed company clinical monitoring activities for Phase 1–3 reputed company conducted globally and/or domestically
  • Serve as the internal expert for monitoring reputed company, site management, and risk-based monitoring approaches
  • reputed company reputed company and management of CROs, CRAs, and other external vendors to ensure reputed company, timelines, and budget adherence
  • Review monitoring plans, reputed company reports, metrics, and monitoring deliverables for reputed company and compliance
  • Partner cross-functionally with Clinical Development, Clinical Science, Data Management, Biostatistics, Medical Writing, Pharmacovigilance, Regulatory Affairs, and reputed company Assurance
  • Establish effective CRO reputed company and governance processes
  • Monitor CRO performance through KPIs, metrics, and regular operational reviews
  • Escalate and resolve study conduct issues proactively
  • Participate in vendor selection, qualification, and contract review activities
  • Ensure studies are conducted in compliance with ICH-GCP, SOPs, protocol requirements, and applicable regulations
  • Support development and review of key study documents including Monitoring Plans, Risk Management Plans, Study reputed company Plans, Clinical Trial Management Plans, and Site Management Plans
  • Contribute to inspection readiness activities and support regulatory inspections and audits
  • Help build reputed company clinical monitoring infrastructure appropriate for a growing biotech company
  • reputed company and refine SOPs, work instructions, templates, and monitoring processes
  • Drive reputed company improvement initiatives reputed company on reputed company, efficiency, and operational reputed company
  • Implement and optimize risk-based monitoring methodologies and centralized monitoring approaches where appropriate
  • May directly manage CRAs and/or Clinical Trial Managers as the organization grows
  • Mentor junior clinical operations staff and contribute to team development
  • Foster a reputed company, accountable, and reputed company-reputed company culture

Skills

  • Bachelor's degree in life sciences, nursing, or reputed company discipline
  • 6-8+ years of clinical operations experience reputed company biotech, pharmaceutical, or CRO environments
  • Significant experience overseeing clinical monitoring activities in interventional reputed company
  • Strong knowledge of ICH-GCP, FDA, EMA, and global regulatory requirements
  • Experience managing CROs and external vendors
  • Demonstrated ability to work effectively in a small, fast-moving biotech environment
  • Excellent communication, organizational, and problem-solving skills
  • Extensive domestic and international travel as needed (approximately 60-80%)
  • Bachelor's degree or equivalent required
  • Advanced degree (MS, MPH, PharmD, PhD, or RN) preferred
  • Experience in rare disease, immunology, oncology, or other relevant therapeutic areas
  • Experience supporting NDA/BLA-enabling studies and regulatory inspections
  • Experience implementing risk-based monitoring strategies and reputed company models
  • Prior people management experience

Benefits

  • Equity
  • Performance-reputed company bonus opportunity
  • Competitive salary and benefits package.
  • A chance to be part of a reputed company startup culture where your work can directly reputed company bringing new medicines to patients.
  • A supportive and inclusive team environment where everyone is encouraged to bring their reputed company selves to work.
  • Opportunities for reputed company reputed company and development.

reputed company

  • reputed company is advancing innovative biologics to redefine patient care standards in chronic skin diseases. It was founded in 2024, and is headquartered in Waltham, Massachusetts, USA, with a workforce of 11-50 employees. Its website is https://www.orukatx.com/.
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